TIMP3 Antikörper (AA 151-211)

Produktnummer ABIN668361

Dieser Anti-TIMP3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TIMP3 in WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human, Ratte und Kaninchen. Dieses Primary Antibody wurde in 5+ Publikationen zitiert.

Kurzübersicht für TIMP3 Antikörper (AA 151-211) (ABIN668361)

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reaktivität: Human, Ratte, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TIMP3 Antikörper

Bindungsspezifität: AA 151-211

Kreuzreaktivität: Human, Kaninchen, Ratte

Homologie: Mouse,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TIMP-3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-TIMP3 Antikörper (ABIN668361)

Han, Liang, Yi, Tan, He, Wang, Li, Wu, Ma, Shi, Guo, Bai: "Long-Term Selenium-Deficient Diet Induces Liver Damage by Altering Hepatocyte Ultrastructure and MMP1/3 and TIMP1/3 Expression in Growing Rats." in: Biological trace element research, (2016) (PubMed).

Peng, Xin, Han, Gao, Gao, Lei, Ji, An, Cao: "Expression and regulative function of tissue inhibitor of metalloproteinase 3 in the goat ovary and its role in cultured granulosa cells." in: Molecular and cellular endocrinology, Vol. 412, pp. 104-15, (2015) (PubMed).

Peng, Gao, Gao, Lei, Han, Xin, An, Cao: "Expression and regulation of tissue inhibitors of metalloproteinases (TIMP1 and TIMP3) in goat oviduct." in: Theriogenology, Vol. 84, Issue 9, pp. 1636-43, (2015) (PubMed).

Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: "The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage." in: Cells, tissues, organs, Vol. 196, Issue 3, pp. 241-50, (2012) (PubMed).

Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: "Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ..." in: Toxicology and applied pharmacology, Vol. 251, Issue 1, pp. 70-8, (2011) (PubMed).

Details zu TIMP3

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Andere Bezeichnung: TIMP-3

Hintergrund:

Synonyms: SFD, K222, K222TA2, HSMRK222, Metalloproteinase inhibitor 3, Protein MIG-5, Tissue inhibitor of metalloproteinases 3, TIMP-3, TIMP3

Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

Gen-ID: 7078

UniProt: P35625